Regon Co. Technologies offers non-exclusive worldwide licenses for advanced technologies in a variety of fields and for a variety of uses. A license under our patents includes rights to different patents, patent applications, market fields and further improvements to the particular technology. Patents that cover additional aspects of invented technologies are pending or issued. Foreign counterparts are issued or pending in Australia, Canada, China, Europe, Russia and Japan. Licensing income received by Regon Technologies Corporation is used to support further research. 

For more information on the licensing program, please contact Dr. Chris Dyanov at: (773) 397-5496


        LICENSING PRODUCTS

· RepelMAGIC^TM Technology – Hydrophobic and Surface-Repellent Solutions and Mixtures.

The RepelMAGIC^TM technology delivers a know-how for the preparation of variable compositions of water- and/or oil-repellant multi-component mixtures containing cyclic molecular compounds, their derivatives and other repellant molecular components. The mixtures can self-assemble forming highly durable ultra-thin layers - instantly upon contact with virtually any kind of surfaces and materials. The properties of the coating are pre-determined upon design depending on the ingredients used. Such technological approach offers better flexibility for water- and oil-repellant surfaces preparation in achieving highly-efficient repellant properties, durability and long-lasting permanent bonding. The RepelMAGIC^TM technology is desirable for specific surface applications and for the preparation of other subsequent types of repellant surfacing solutions such as paints, sealing agents, textiles, electronics, medical/surgical devices, solar cells, sport/occupational wear and else.

This technology relates to hydrophobic (water-repellent) and oil-repellant coating compositions which have highest application flexibility, relatively low toxicity, produces highly durable solids coatings, and has a superb external appearance, curability and long-lasting properties ensured by the permanent-type bonding. 

The RepelMAGIC^TM technology can serve for a wide variety of military applications - from clothing to plane surfaces de-icing.

 

· NanoFIX^TM Technology – Method and Substrates for Covalent Attachment and Encapsulation of Biological, Chemical and Physical Substances.

NanoFIX^TM technology allows for the preparation of variaety of compositions of multi-component derivatization mixtures, multi-molecular compounds and other molecular components with demonstrating specific derivatization-, chemical-, repellant- and optical properties. It offers superior design flexibility in achieving extreme surface-attachment durability, outstanding chemical reactivity toward highly specific chemical groups or desirably universal ranges, chosen degree of water-repellency and other physical, and chemical properties for long-lasting (permanent) bonding. The technology opens a wide avenue for specific surface applications for preparation, attachment and impregnation of compositions used in biological, medical, mechanical and industrial devices, sensors or applications. The NanoFIX^TM technology is intended for the derivatization of surfaces with chemically-reactive groups for the attachment of biomolecules, pharmaceutical agents and/or other components, for manufacturing micro-devices, serving for detection, energy-delivering and energy-transferring purposes, and for permeable microencapsulation/impregnation of small objects of biological and/or mechanical nature by the means of nanolayers and covalent bonds formation.

 

· EnerJAZZY^TM Technology Methods and Devices for Energy-Assisted Enhancement of the Bio-molecular Interactions.

A method and devices are under patenting for enhancement of a wide range of bio-molecular interactions, reactions and processes via wave irradiation of specific forms, intensity and conditions. Its control within a broad range of parameters allows for incredibly original and efficient practical modification of common or original bio-molecular properties and functions – resulting from the controlled energy exposure from external sources. Some of the technology advances include the following:

† Enhanced annealing and structural interactions between the nucleic acids (RNA and/or DNA, oligonucleotides, modified nucleic acids, derivatives and synthetic analogs) – with efficiencies that are impossible to achieve by any other standard-practice means.

† Improved interactions and functions of enzymes, enzymatic conditions and processes. High-impact enhancement of nucleic-acid synthesis reactions due to energy-assisted enzymatic performance and 3-D structural modification of the nucleic acids' configuration.

† Structural and conformational modification of nucleic acids leading to the enhancement of nucleic-acid–protein interactions aiding gene investigation studies with high impact on single-cells gene libraries preparations, laser micro-dissection (LMD), gene-microarrays and gene-detection devices.

† High improvement of the functions of microfluidic devices, sensors and reactions.

· Nucleic-acid Profiling by Oligonucleotide Hybridization Fingerprinting 

Gene expression profiling is one of the many applications that have benefited from the massively parallel nucleic acid detection capability of DNA microarrays. Although development started over 20 years ago, efficient practical implementation of the microarray technology is lagging behind its advances, and immense medical and commercial potential. Current expression arrays, are still expensive and inflexible. They are custom-designed for each organism and they do not offer the possibility of incorporating updated genomic information without production of a new chip. One possible solution is the development of a universal chip, consisting of all 4ⁿ possible DNA sequences of length n capable of profiling (i.e. “fingerprinting”) each and every nucleic acid molecule representing any gene in all or a group of organisms. Studying different organisms or new genes requires modifications to the hybridization pattern analysis software as well. 

GeneENCODE^TM technology was pioneered by Dr. Dyanov in 1993 and consequentially advanced to the current level to become capable of fingerprinting, detecting and isolating any known- or suggested genetic fragment originating from any biological source – independent from the background genetic content. It allows for monitoring of tens of thousands genes from hundreds of organisms simultaneously by one universal microarray. In its format, it possesses the power to revolutionize medical diagnostics, disease monitoring and National bio-security detection.